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Exploring the Causal Links Between Toxoplasma gondii Infection and Risk of Brain Tumors: A Bidirectional Mendelian Randomization Analysis.

Brain and behavior - 1 Feb 2026

Shi Pengqiang, Wei Gangao, Li Zhenwei, Du Baoshun, Zhang Guodong, Zhang Jiaqi, Wang Yungang, Chen Yunchao, Cheng Zhang, Cheng Zhenguo

Abstract excerpt

BACKGROUND: Toxoplasma gondii (T. gondii) is a ubiquitous protozoan parasite capable of establishing lifelong latent infections in the central nervous system. Previous epidemiological studies have suggested a potential association between T. gondii infection and an increased risk of brain cancer, but the causal relationship remains unclear. METHODS: We conducted a bidirectional Mendelian randomization (MR) study...

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Identifiers

PMID: 41612813
DOI: 10.1002/brb3.71239
PMCID: PMC12856237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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