Article
Testing for causality between systematically identified risk factors and glioma: a Mendelian randomization study.
BMC cancer - 3 Jun 2020
Howell A E, Robinson J W, Wootton R E, McAleenan A, Tsavachidis S, Ostrom Q T, Bondy M, Armstrong G, Relton C, Haycock P, Martin R M, Zheng J, Kurian K M
Abstract excerpt
BACKGROUND: Whilst epidemiological studies have provided evidence of associations between certain risk factors and glioma onset, inferring causality has proven challenging. Using Mendelian randomization (MR), we assessed whether associations of 36 reported glioma risk factors showed evidence of a causal relationship. METHODS: We performed a systematic search of MEDLINE from inception to October 2018 to identify...
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