Article
Genetic association of lipids and lipid-lowering drug target genes with Endometrial carcinoma: a drug target Mendelian randomization study.
Frontiers in endocrinology - 1 Jan 2024
Yang Zhehan, Chen Junpan, Wen Minghao, Lei Jiayuan, Zeng Ming, Li Sichen, Long Yao, Zhou Zhiyi, Wang Chunyan
Abstract excerpt
Background: Aberrant lipid metabolism is intricately linked to the development of endometrial cancer, and statin lipid-lowering medications are regarded as promising adjunctive therapies for future management of this malignancy. This study employed Mendelian randomization (MR) to explore the causal association between lipid traits and endometrial cancer while assessing the potential impact of drug targets on...
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