Article
Reinforcement amid genetic diversity in the Candida albicans biofilm regulatory network.
PLoS pathogens - 1 Jan 2023
Cravener Max V, Do Eunsoo, May Gemma, Zarnowski Robert, Andes David R, McManus C Joel, Mitchell Aaron P
Abstract excerpt
Biofilms of the fungal pathogen Candida albicans include abundant long filaments called hyphae. These cells express hypha-associated genes, which specify diverse virulence functions including surface adhesins that ensure biofilm integrity. Biofilm formation, virulence, and hypha-associated gene expression all depend upon the transcription factor Efg1. This transcription factor has been characterized extensively...
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