Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The influence of a type I antifreeze protein and its mutants on methane hydrate adsorption-inhibition: A molecular dynamics simulation study.

The Journal of chemical physics - 21 May 2026

Cui Shaoli, Liu Fengxiang, Zhang Tianli, Du Binghui, Wang Guangnian, Lu Jiarui, Han Di, Liu Taigang, Wang Meiting, He Guangjie, Xu Yongtao

Abstract excerpt

The formation of methane hydrates in oil and gas pipelines poses significant challenges to flow assurance, driving the urgent need for efficient and environmentally friendly kinetic hydrate inhibitors. The moderately active type I winter flounder antifreeze protein (wfAFP) exerts its ability to inhibit methane hydrate growth by binding to methane hydrate cages via specific amino acids [Thr-(i), Ala-(i+4),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adsorption
Share to Flounder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydrogen Bonding

Share to Methane

Share to Molecular Dynamics Simulation

Share to Mutation

Source

Identifiers

PMID: 42138410
DOI: 10.1063/5.0327480

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The influence of a type I antifreeze protein and its mutants on methane hydrate adsorption-inhibition: A molecular dynamics simulation study.PMID 42138410Read ↗

Computational Study of Differences between Antifreeze Activity of Type-III Antifreeze Protein from Ocean Pout and Its Mutant.Semantic proximity Read ↗

Effect of a mutation on the structure and dynamics of an alpha-helical antifreeze protein in water and ice.Semantic proximity Read ↗

Biophysical and biochemical aspects of antifreeze proteins: Using computational tools to extract atomistic information.Semantic proximity Read ↗

Growth inhibition mechanism of an ice-water interface by a mutant of winter flounder antifreeze protein: a molecular dynamics study.Semantic proximity Read ↗

Conformational and hydration properties modulate ice recognition by type I antifreeze protein and its mutants.Semantic proximity Read ↗

Structural investigation, computational analysis, and theoretical cryoprotectant approach of antifreeze protein type IV mutants.Semantic proximity Read ↗

Structure of type I antifreeze protein and mutants in supercooled water.Semantic proximity Read ↗

Type I 'antifreeze' proteins. Structure-activity studies and mechanisms of ice growth inhibition.Semantic proximity Read ↗

Characterization of microbial antifreeze protein with intermediate activity suggests that a bound-water network is essential for hyperactivity.Semantic proximity Read ↗

Engineering a naturally inactive isoform of type III antifreeze protein into one that can stop the growth of ice.Semantic proximity Read ↗

Mechanisms of antifreeze proteins investigated via the site-directed spin labeling technique.Semantic proximity Read ↗

Polypentagonal ice-like water networks emerge solely in an activity-improved variant of ice-binding protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.