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Article

Conformational and hydration properties modulate ice recognition by type I antifreeze protein and its mutants.

Physical chemistry chemical physics : PCCP - 10 May 2017

Chakraborty Sandipan, Jana Biman

Abstract excerpt

The mechanism of ice recognition by antifreeze protein (AFP) is a topic of recent interest. Here, using equilibrium simulations and free energy calculations, we provide structural rationale to the observed experimental anomalies on type I AFP (wfAFP isoform HPLC6) and its mutants as well as probe the molecular origin of ice recognition by them. Our results clearly demonstrate that the interplay between the...

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Identifiers

PMID: 28435965
DOI: 10.1039/c7cp00221a

Genes

AFP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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