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Article

Multivariate genetic architecture of age-related eye disease.

PloS one - 1 Jan 2026

Gao Luqi, Wang Qihao, Zhu Chao

Abstract excerpt

At present, the genetic architecture underlying traits linked to Age-related eye disease (ARED) remains largely unexplored. We utilized Genomic Structural Equation Modeling (Genomic-SEM) and various Post-processing analysis of Genome-Wide Association Studies (GWAS) to identify statistically prioritized candidate single nucleotide polymorphisms (SNPs) associated with independent ARED variants. A total of 11...

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PMID: 42133706
DOI: 10.1371/journal.pone.0349199
PMCID: PMC13175492

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