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Article

Effects of a Mitochondrial Genetic Variant on Sevoflurane Hypersensitivity.

Anesthesiology - 1 Jun 2026

Sanz-Pons Javier, Aladrén-Herrer Celia, Ortigoza-Escobar Juan Darío, López-Gallardo Ester, Martín-Navarro Antonio, Lanz-Martínez Carlos Alberto, Camacho-Medina Yohanna Alexandra, Fernández-González Isabel, Urbano Javier, Montoya Julio, Hernández-Castillo Yaremy, Bayona-Bafaluy Pilar, Ruiz-Pesini Eduardo

Abstract excerpt

BACKGROUND: Recently, various anesthesiology societies have reported cases involving pediatric patients of Venezuelan origin who underwent surgery under general anesthesia and subsequently developed serious neurologic impairment or died. However, the cause of this condition was unknown. METHODS: Clinical and genetic studies were conducted on seven patients who experienced severe acute neurologic deterioration...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42117732
DOI: 10.1097/ALN.0000000000006029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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