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Article

Association between well-characterized gene polymorphisms and the hypnosis response caused by sevoflurane-induced anaesthesia.

Journal of clinical pharmacy and therapeutics - 1 Dec 2020

Chen Ming-Hua, Ouyang Wen, Xia Yu-Hao, Zeng You-Jie, Wang Sai-Ying, Duan Kai-Ming, Fang Chao

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVE: Sevoflurane is the most widely used volatile anaesthetic in clinical practice. It exhibits a hypnotic (unconsciousness) effect and causes a loss of reaction to noxious stimuli (immobility). However, to date, the mechanism of action of sevoflurane is poorly understood. In this study, we explored the effects of genetic variations on sevoflurane-induced hypnosis. METHODS: Sixty-six SNPs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Nerve Tissue Proteins

Share to Polymorphism, Single Nucleotide

Share to Receptors, N-Methyl-D-Aspartate

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Identifiers

PMID: 33016519
DOI: 10.1111/jcpt.13275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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