Article
Pharmacogenetics and anesthetic drugs.
Current clinical pharmacology - 1 May 2012
Chidambaran Vidya, Ngamprasertwong Pornswan, Vinks Alexander A, Sadhasivam Senthilkumar
Abstract excerpt
The incidence and potential for serious adverse drug reactions (SADRs) in anesthesia are high due to the narrow therapeutic indices of anesthetic and analgesic drugs and high interindividual variability in drug responses. Genetic factors contribute to a majority of these SADRs. Pharmacogenetics (PG), the study of genetic effects on drug action, is strongly related to the field of anesthesia; historically,...
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