Islet autoantibodies are associated with HLA-DQ genotypes in Han Chinese patients with type 1 diabetes and their relatives.

doi:10.1111/j.1399-0039.2007.00916.x

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Article

Islet autoantibodies are associated with HLA-DQ genotypes in Han Chinese patients with type 1 diabetes and their relatives.

Tissue antigens - 1 Nov 2007

Wang J-P, Zhou Z-G, Lin J, Huang G, Zhang C, Yang L, Yuan Y, Zhou H-F, Zhou M, Hou C, Zhou W-D, Peng H, Hagopian W A

Abstract excerpt

The objective of this study was to explore the relationship between islet autoantibodies of glutamic acid decarboxylase (GADA), islet antigen-2A (IA-2A), insulin autoantibody (IAA), and human leukocyte antigen (HLA)-DQ genotypes in type 1 diabetes (T1D) patients and their first-degree relatives (FDRs). Cross-sectional and case-control study. Four hundred and ninety-five T1D patients, 419 FDRs, and 376 control...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Asian People
Autoantibodies
Case-Control Studies
Child
Child, Preschool
China
Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Diabetes Mellitus, Type 1

Family

Female

Gene Frequency

Genetic Predisposition to Disease

Genotype

Glutamate Decarboxylase

Source

Open in PubMed

Identifiers

PMID: 17919266
DOI: 10.1111/j.1399-0039.2007.00916.x

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