Article
CTLA-4+49 A/G polymorphism and antiglutamic acid decarboxylase antibody-associated encephalopathy in Taiwanese children.
Brain & development - 1 Apr 2016
Lin Jainn-Jim, Lin Kuang-Lin, Wang Yu, Wang Huei-Shyong, Hsia Shao-Hsuan, Chang Luan-Yin
Abstract excerpt
BACKGROUND: Anti-glutamic acid decarboxylase antibodies are associated with encephalopathy, an autoimmune central nervous system inflammatory disease. The cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4)+49 A/G polymorphism has been shown to confer genetic susceptibility to positive anti-glutamic acid decarboxylase antibodies in patients with type 1 diabetes mellitus in Japan. We aimed to investigate the...
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