Article
HLA genotyping and clinical characteristics of early-onset and late-onset anti-LGI1 encephalitis: a single-center cohort study in China.
Frontiers in immunology - 1 Jan 2026
Ni Pinfei, Fan Siyuan, Zhang Han, Bai Lin, Yang Zhuo, Yang Xinzhuang, Ren Haitao, Lu Qiang, Xiao Meng, Guan Hongzhi
Abstract excerpt
Objectives: To investigate the human leukocyte antigen (HLA) associations and clinical characteristics of anti-Leucine-rich glioma-inactivated 1 (LGI1) encephalitis in a Chinese cohort, focusing on potential differences between early-onset and late-onset patients. Methods: Eighty patients diagnosed with anti-LGI1 encephalitis at Peking Union Medical College Hospital between the years 2016 and 2024 were included....
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