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Article

Multiomics and Genomic Alteration Characterization Identifies VDAC1 as a Mitochondrial-Associated Biomarker in Pancreatic Cancer.

Human mutation - 1 Jan 2026

Sun Wanliang, Wang Yifei, Qiao Xuxu, Zhou Shuo, Liu Zhong, Yang Song, Zhang Dengyong, Wang Dongdong, Zhou Hu, Qi Feiyu, Zhang Mingrui, Wu Binquan, Tan Yi, Cen Lijun, Zhang Biao

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is characterized by aggressive biological behavior and limited therapeutic responsiveness. Identifying genetically and biologically interpretable biomarkers remains critical for improving molecular stratification of this malignancy. Here, we performed an integrative analysis combining bulk transcriptomics, genomic alteration profiling, immune-response modeling, and...

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Share to Carcinoma, Pancreatic Ductal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 42111501
DOI: 10.1155/humu/5510306
PMCID: PMC13150345

Genes

VDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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