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Article

Overexpressed VDAC1 in breast cancer as a novel prognostic biomarker and correlates with immune infiltrates

22 Jun 2022

Abstract excerpt

BACKGROUND: More and more evidence suggests that cancer is a mitochondrial metabolic disease recently and mitochondria dysfunction is critical to tumorigenesis. As a gatekeeper of mitochondria, the voltage-dependent anion channel 1 (VDAC1) is associated with the development of breast cancer (BC). However, its potential mechanism and clinical significance remain unclear; thus, in this research, we aimed to explore...

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PMID: 35729567
DOI: 10.1186/s12957-022-02667-2

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