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Article

Common disorders are quantitative traits.

Nature reviews. Genetics - 1 Dec 2009

Plomin Robert, Haworth Claire M A, Davis Oliver S P

Abstract excerpt

After drifting apart for 100 years, the two worlds of genetics - quantitative genetics and molecular genetics - are finally coming together in genome-wide association (GWA) research, which shows that the heritability of complex traits and common disorders is due to multiple genes of small effect size. We highlight a polygenic framework, supported by recent GWA research, in which qualitative disorders can be...

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Identifiers

PMID: 19859063
DOI: 10.1038/nrg2670

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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