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Article

Prognostic and therapeutic roles of specific genotypes through target-gene sequencing on gastroenteropancreatic neuroendocrine carcinoma.

The oncologist - 8 May 2026

Zhang Jianwei, Zhang Panpan, Zhang Yanyan, Hu Qiaomian, Li Jie, Zhang Xiaotian, Li Jian, Wang Xicheng, Zhou Jun, Lu Zhihao, Peng Zhi, Sun Yu, Wang Sha, Lu Ming, Shen Lin

Abstract excerpt

PURPOSE: Despite emerging genomic discoveries, few have been translated into practical management strategies for people with gastroenteropancreatic neuroendocrine carcinoma (GEPNEC). This study aims to identify key genes and their potential clinical relevance to improve care for this patient group. METHODS: In the analytical cohort, we reported high-frequency alteration genes, significantly mutated genes, and...

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Identifiers

PMID: 42104934
DOI: 10.1093/oncolo/oyag185
PMCID: PMC13215382

Genes

RB1
TP53
APC
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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