Article
Genome-Wide Screen for Genes Involved in Caenorhabditis elegans Developmentally Timed Sleep.
G3 (Bethesda, Md.) - 7 Sept 2017
Huang Huiyan, Zhu Chen-Tseh, Skuja Lukas L, Hayden Dustin J, Hart Anne C
Abstract excerpt
In Caenorhabditis elegans, Notch signaling regulates developmentally timed sleep during the transition from L4 larval stage to adulthood (L4/A) . To identify core sleep pathways and to find genes acting downstream of Notch signaling, we undertook the first genome-wide, classical genetic screen focused on C. elegans developmentally timed sleep. To increase screen efficiency, we first looked for mutations that...
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