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Article

Stochastic growth and ligand-receptor interaction-mediated stabilization generate stereotyped dendritic arbors.

Nature neuroscience - 1 Jun 2026

Shi Rebecca, Ho Xue Yan, Tao Li, Bayless-Edwards Landon, Taylor Caitlin A, Zhao Ting, Zou Wei, Lizzappi Malcolm, Eichel Kelsie, Mao Tianyi, Shen Kang

Abstract excerpt

Stereotyped dendritic arbors are shaped by dynamic and stochastic growth during neuronal development. It remains unclear how guidance receptors and ligands coordinate branch dynamic growth, retraction and stabilization to specify dendritic arbors. We previously showed that extracellular adhesion ligand SAX-7/LICAM dictates the elaborate and stereotyped shape of the Caenorhabditis elegans PVD sensory dendrite via...

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Identifiers

PMID: 42082815
DOI: 10.1038/s41593-026-02278-0
PMCID: PMC13246438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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