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Article

Endocytosis restricts dendrite branching via removing ectopically localized branching ligands.

Nature communications - 7 Nov 2024

Fang Jie, Jiang Wenli, Zhao Weixia, Wang Jie, Cao Beibei, Wang Nan, Chen Baohui, Wang Chao, Zou Wei

Abstract excerpt

Neurons often grow highly branched and cell-type specific dendrite morphologies to receive and integrate information, which is the basis of precise neural circuit formation. Previous studies have identified numerous mechanisms that promote dendrite branching. In contrast, it is much less understood how this process is negatively regulated. Here we show that EAT-17/EVI5 acts together with the dynein adaptor...

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Identifiers

PMID: 39511227
DOI: 10.1038/s41467-024-53970-3
PMCID: PMC11544243

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