Article
Dynein and EFF-1 control dendrite morphology by regulating the localization pattern of SAX-7 in epidermal cells.
Journal of cell science - 1 Dec 2017
Zhu Ting, Liang Xing, Wang Xiang-Ming, Shen Kang
Abstract excerpt
Our previous work showed that the cell adhesion molecule SAX-7 forms an elaborate pattern in Caenorhabditis elegans epidermal cells, which instructs PVD dendrite branching. However, the molecular mechanism forming the SAX-7 pattern in the epidermis is not fully understood. Here, we report that the dynein light intermediate chain DLI-1 and the fusogen EFF-1 are required in epidermal cells to pattern SAX-7. While...
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