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Article

Neuron tracing and quantitative analyses of dendritic architecture reveal symmetrical three-way-junctions and phenotypes of git-1 in C. elegans.

PLoS computational biology - 1 Jul 2021

Yuval Omer, Iosilevskii Yael, Meledin Anna, Podbilewicz Benjamin, Shemesh Tom

Abstract excerpt

Complex dendritic trees are a distinctive feature of neurons. Alterations to dendritic morphology are associated with developmental, behavioral and neurodegenerative changes. The highly-arborized PVD neuron of C. elegans serves as a model to study dendritic patterning; however, quantitative, objective and automated analyses of PVD morphology are missing. Here, we present a method for neuronal feature extraction,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34280180
DOI: 10.1371/journal.pcbi.1009185
PMCID: PMC8321406

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