Article
Non-invasive single-cell biomechanical analysis using live-imaging datasets.
Journal of cell science - 1 Sept 2016
Pearson Yanthe E, Lund Amanda W, Lin Alex W H, Ng Chee P, Alsuwaidi Aysha, Azzeh Sara, Gater Deborah L, Teo Jeremy C M
Abstract excerpt
The physiological state of a cell is governed by a multitude of processes and can be described by a combination of mechanical, spatial and temporal properties. Quantifying cell dynamics at multiple scales is essential for comprehensive studies of cellular function, and remains a challenge for traditional end-point assays. We introduce an efficient, non-invasive computational tool that takes time-lapse images as...
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