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Article

High-throughput cell mechanical phenotyping for label-free titration assays of cytoskeletal modifications.

Cytoskeleton (Hoboken, N.J.) - 1 Aug 2017

Golfier Stefan, Rosendahl Philipp, Mietke Alexander, Herbig Maik, Guck Jochen, Otto Oliver

Abstract excerpt

The mechanical fingerprint of cells is inherently linked to the structure of the cytoskeleton and can serve as a label-free marker for cell homeostasis or pathologic states. How cytoskeletal composition affects the physical response of cells to external loads has been intensively studied with a spectrum of techniques, yet quantitative and statistically powerful investigations in the form of titration assays are...

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Identifiers

PMID: 28445605
DOI: 10.1002/cm.21369
PMCID: PMC5601209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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