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Article

Variant-to-Biomarker Pathways in Peripheral Artery Disease: Multiomics Integration and Clinical Translation.

Human mutation - 1 Jan 2026

Wang Wanting, Zhao Gang, Yang Changxin, Chang Siyao

Abstract excerpt

Peripheral artery disease (PAD) is a prevalent, disabling manifestation of systemic atherosclerosis that carries high risks of major adverse cardiovascular and limb events, yet remains incompletely explained by conventional risk factors and haemodynamic indices. Although genome-wide association studies have nominated reproducible susceptibility loci and high-throughput profiling has expanded the landscape of...

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PMID: 42063615
DOI: 10.1155/humu/1908331
PMCID: PMC13127234

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