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Article

Abnormal Sperm Morphology in Lodpr/lncRNA-HSVIII Knockout Mice with Advancing Age.

Reproductive sciences (Thousand Oaks, Calif.) - 1 May 2026

Tippramuan Pummarin, Yujia Luo, Satoh Yui, Kitada Kazuhiro, Fujimori Chika, Kimura Atsushi P

Abstract excerpt

A mouse testis-specific long noncoding RNA, Lodpr/lncRNA-HSVIII, is expressed in germ cells and Leydig cells; however, its functional role remains uncharacterized. To clarify the physiological role, we generated Lodpr/lncRNA-HSVIII knockout (KO) mice using the CRISPR/Cas9 technology. Although Lodpr/lncRNA-HSVIII KO mice did not exhibit infertility, their phenotypic traits were documented at 2 months and 6 months...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 42062700
DOI: 10.1007/s43032-026-02103-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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