Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice.

Cells - 28 Mar 2020

Abbasi Ferheen, Kodani Mayo, Emori Chihiro, Kiyozumi Daiji, Mori Masashi, Fujihara Yoshitaka, Ikawa Masahito

Abstract excerpt

There are over 200 genes that are predicted to be solely expressed in the oocyte and ovary, and thousands more that have expression patterns in the female reproductive tract. Unfortunately, many of their physiological functions, such as their roles in oogenesis or fertilization, have yet to be elucidated. Previous knockout (KO) mice studies have proven that many of the genes that were once thought to be essential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Conserved Sequence
Share to CRISPR-Cas Systems

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fertility

Share to Gene Editing

Share to Mice, Mutant Strains

Share to Multigene Family

Share to Pregnancy Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 32231122
DOI: 10.3390/cells9040821
PMCID: PMC7226750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice.PMID 32231122Read ↗

CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†Semantic proximity Read ↗

CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†Semantic proximity Read ↗

CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecunditySemantic proximity Read ↗

CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in miceSemantic proximity Read ↗

Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasetsSemantic proximity Read ↗

Deconstructing mammalian reproduction: using knockouts to define fertility pathwaysSemantic proximity Read ↗

Oocyte-specific Wee1-like protein kinase 2 is dispensable for fertility in miceSemantic proximity Read ↗

Gene knockouts that cause female infertility: search for novel contraceptive targets.Semantic proximity Read ↗

Genomewide Discovery and Classification of Candidate Ovarian Fertility Genes in the MouseSemantic proximity Read ↗

CPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency.Semantic proximity Read ↗

Individual disruption of 12 testis-enriched genes via the CRISPR/Cas9 system does not affect the fertility of male miceSemantic proximity Read ↗

Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice†Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.