Article
Causal Association Between Commonly Used Medicines and Diabetes-Related Eye Diseases: Univariable and Multivariable Mendelian Randomization Study.
Journal of diabetes research - 1 Jan 2026
Wang Yu, Cheng Chak Kwong, A Lamusi, Jin Mingyue, Wang Chang
Abstract excerpt
BACKGROUND: Diabetic patients require long-term polypharmacy, yet the causal effects of these medications on ocular complications-specifically diabetic retinopathy (DR), diabetic maculopathy (DMac), and glaucoma-remain unclear due to confounding in observational studies. METHODS: We performed a Mendelian randomization (MR) study using GWAS summary statistics for 23 common medication classes and five diabetic eye...
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