Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Correlation and Mendelian Randomization Analyses Reveal Causal Links Between Metabolic-Associated Diseases or Risk Factors and Major Eye Diseases.

Current eye research - 1 Mar 2026

Tang Jialing, Chen Junjie, Li Zhaohuai, Zhang Genxian, Zhu Lei, Li He, Su Wenru, Qin Shuyan

Abstract excerpt

PURPOSE: This study aims to elucidate the causal relationships and shared genetic architecture between metabolic-associated diseases and risk factors-including hypertension, type 1 diabetes (T1D), type 2 diabetes (T2D), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and body mass index (BMI)-and primary vision-threatening eye disorders, involving glaucoma, cataracts,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cataract
Share to Eye Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Macular Degeneration

Share to Mendelian Randomization Analysis

Share to Metabolic Diseases

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Identifiers

PMID: 41449919
DOI: 10.1080/02713683.2025.2585338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Correlation and Mendelian Randomization Analyses Reveal Causal Links Between Metabolic-Associated Diseases or Risk Factors and Major Eye Diseases.PMID 41449919Read ↗

Dissecting causal associations of type 2 diabetes with 111 types of ocular conditions: a Mendelian randomization studySemantic proximity Read ↗

Mendelian randomization study reveals a population-specific putative causal effect of type 2 diabetes in risk of cataract.Semantic proximity Read ↗

Causal relationship between glycemic traits and inflammatory eye diseases and their complications, and myopia: a Mendelian randomization analysisSemantic proximity Read ↗

Thyroid Function, Diabetes, and Common Age-Related Eye Diseases: A Mendelian Randomization Study.Semantic proximity Read ↗

Association of Behavioral and Clinical Risk Factors With Cataract: A Two-Sample Mendelian Randomization Study.Semantic proximity Read ↗

The putative causal effect of type 2 diabetes in risk of cataract: a Mendelian randomization study in East AsianSemantic proximity Read ↗

Sex differences in the risk of cataract associated with type 2 diabetes: a Mendelian randomization studySemantic proximity Read ↗

The causal effect of hypertension, intraocular pressure, and diabetic retinopathy: a Mendelian randomization studySemantic proximity Read ↗

Causal Associations of Glaucoma and Age-Related Macular Degeneration with Cataract: A Bidirectional Two-Sample Mendelian Randomisation Study.Semantic proximity Read ↗

A Genetic Perspective on Diabetic Complications: A Mendelian Randomization Study on the Increased Risk of Cataracts in Type 1 DiabetesSemantic proximity Read ↗

Metabolic and lifestyle factors in relation to senile cataract: a Mendelian randomization study.Semantic proximity Read ↗

Causal associations between smoking and ocular diseases: a Mendelian randomization studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.