Article
Thyroid Function, Diabetes, and Common Age-Related Eye Diseases: A Mendelian Randomization Study.
Thyroid : official journal of the American Thyroid Association - 1 Nov 2024
Ellervik Christina, Boulakh Lena, Teumer Alexander, Marouli Eirini, Kuś Aleksander, Buch Hesgaard Helena, Heegaard Steffen, Blankers Lizette, Sterenborg Rosalie, Åsvold Bjørn Olav, Winkler Thomas Wolfgang, Medici Marco, Kjaergaard Alisa Devedzic
Abstract excerpt
Background: Previous Mendelian randomization (MR) studies showed an association between hypothyroidism and cataract and between high-normal free thyroxine (FT4) and late age-related macular degeneration (AMD), but not between FT4, thyroid stimulating hormone (TSH), or hyperthyroidism and diabetic retinopathy or cataract. These studies included a limited number of genetic variants for thyroid function and did not...
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