Back to search

Article

Causal relationship between lipid-lowering drugs and ocular disorders: A drug-targeted Mendelian randomization study

2024-08-13

Abstract excerpt

<title>Abstract</title> <p>Background Most ocular diseases are associated with lipid metabolism, but the exact mechanisms are unclear. Statins, PCSK9 inhibitors and NPC1L1 inhibitors are common lipid-modulating agents. The aim of this study was to explore the causal relationship between common lipid-lowering drugs and ocular diseases through Mendelian randomization analysis. Methods In this study, we used the s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f536109e-597e-57d6-9c91-454ba17a7180
DOI
10.21203/rs.3.rs-4437336/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Causal relationship between lipid-lowering drugs and ocular disorders: A drug-targeted Mendelian randomization studyDOI 10.21203/rs.3.rs-4437336/v1
Application of mendelian randomization in ocular diseases: a review.Semantic proximity
Statins as a risk factor for diabetic retinopathy: a Mendelian randomization and cross-sectional observational studySemantic proximity
Causal associations between smoking and ocular diseases: a Mendelian randomization studySemantic proximity
Mendelian randomization analyses in ocular disease: a powerful approach to causal inference with human genetic data.Semantic proximity
Genetic Association between Lipid-Regulating Drug Targets and Diabetic Retinopathy: A Drug Target Mendelian Randomization StudySemantic proximity
Association between lipid-lowering drugs and allergic diseases: A Mendelian randomization studySemantic proximity
Genetic Evidence for Causal Effects of Lipid-lowering Drug Targets on Primary Sjögren's Syndrome Risk: A Mendelian Randomization Study.Semantic proximity
Natural active ingredients targeted inflammatory cytokines and major blinding eye diseases: a two-sample Mendelian randomization and molecular docking analysisSemantic proximity
Causal relationship between glycemic traits and inflammatory eye diseases and their complications, and myopia: a Mendelian randomization analysisSemantic proximity
Genetic correlation between circulating cytokines and risk of three ophthalmic diseases: a bidirectional two-sample Mendelian randomization study.Semantic proximity
Genetic Correlation and Mendelian Randomization Analyses Reveal Causal Links Between Metabolic-Associated Diseases or Risk Factors and Major Eye Diseases.Semantic proximity
Causal effects of circulating lipids and lipid-lowering drugs on the risk of atopic dermatitis: a mendelian randomization study.Semantic proximity
Select a neighboring publication to make it the new centre.