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Article

Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis.

Translational vision science & technology - 4 Nov 2024

Liu Huan, Wang Feiyan, Hu Ziqing, Wei Jing

Abstract excerpt

Purpose: This study aimed to investigate the causal effect of plasma proteins on diabetic retinopathy (DR) risk and identify potential drug targets for this disease. Methods: Two-sample Mendelian randomization was performed to explore potential drug targets for DR. A total of 734 proteins were selected as instrumental variables. The Steiger filtering test and colocalization analysis were conducted to determine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39541108
DOI: 10.1167/tvst.13.11.17
PMCID: PMC11572760

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