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Article

Exploring the causal effect of genetically predicted blood and cerebrospinal fluid metabolites and metabolic pathways on intracranial aneurysm.

The Journal of international medical research - 1 Apr 2026

Ding Lu, Cao Wei, Zhou Zhou, Mei Zhaojun, Chen Bo, Lu Xinyu, Chen Wei

Abstract excerpt

ObjectivePrevious studies have identified significant alterations in metabolites in patients with intracranial aneurysm. This study aimed to evaluate the causal relationships of metabolites in both blood and cerebrospinal fluid with intracranial aneurysm at the genetic level using bidirectional Mendelian randomization analysis.MethodsGenetic instrumental variables for 1400 blood metabolites were obtained from a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42050911
DOI: 10.1177/03000605261442755
PMCID: PMC13145066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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