Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regular exercise modifies the effects of 12 LDL-C SNPs on cardiovascular disease risk: KoGES.

Lipids in health and disease - 27 Apr 2026

Park Yon Chul, Cho Ahhyun, Kim Yong-Sang, Kim Yonghwan, Park Jae-Min, Han Kunhee, Kim Bomtaeck, Kim Kwangyoon, Shin Junghwa, Kwon Yu-Jin, Choi Ja-Eun, Hong Kyung-Won

Abstract excerpt

BACKGROUND: Cardiovascular disease risk is significantly driven by dyslipidemia, making it a crucial target for clinical management; however, the translation of low-density lipoprotein cholesterol (LDL-C)-related genetic susceptibility into clinical events is complex. Although regular physical activity improves cardiometabolic health, its effects on LDL-C concentrations are often modest. The present study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, LDL

Share to Dyslipidemias

Share to Exercise

Share to Republic of Korea

Share to Risk Factors

Share to Triglycerides

Source

Open in PubMed Open full text

Identifiers

PMID: 42046085
DOI: 10.1186/s12944-026-02963-w
PMCID: PMC13255458

Genes

DHODH
HP
HPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regular exercise modifies the effects of 12 LDL-C SNPs on cardiovascular disease risk: KoGES.PMID 42046085Read ↗

A Whole-Genome Approach Discovers Novel Genetic and Non-Genetic Variance Components Modulated by Lifestyle for Cardiovascular HealthSemantic proximity Read ↗

Endothelial cell-related genetic variants identify LDL cholesterol-sensitive individuals who derive greater benefit from aggressive lipid lowering.Semantic proximity Read ↗

Dyslipidaemia—Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular DiseaseSemantic proximity Read ↗

Exploring gene-activity interplay in cardiovascular disease: is feasible to mitigate genetic risk through physical activity?Semantic proximity Read ↗

Physical activity, genetic predisposition, and incident cardiovascular disease: Prospective analyses of the UK BiobankSemantic proximity Read ↗

A Western-style diet interacts with genetic variants of the LDL receptor to hyper-LDL cholesterolemia in Korean adultsSemantic proximity Read ↗

Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management.Semantic proximity Read ↗

Whole-Genome Approach Discovers Novel Genetic and Nongenetic Variance Components Modulated by Lifestyle for Cardiovascular Health.Semantic proximity Read ↗

Impact of genetic markers related to hyper-HDL cholesterol on the prevalence of myocardial infarction: a KoGES study.Semantic proximity Read ↗

Gene-drug interactions identify genomic loci that enhance statin effectiveness in lowering LDL cholesterolSemantic proximity Read ↗

Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.Semantic proximity Read ↗

Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.