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Article

Impact of genetic markers related to hyper-HDL cholesterol on the prevalence of myocardial infarction: a KoGES study.

Journal of lipid research - 1 Apr 2025

Lee Sung-Bum, Hong Kyung-Won, Park Byoungjin, Jung Dong-Hyuk

Abstract excerpt

Recent studies have shown that hyper-high-density lipoprotein cholesterol (HDL-C) is associated with cardiovascular disease risk and all-cause mortality, a phenomenon known as the HDL-C paradox. Several genes have been reported to show relationships between increased HDL-C and myocardial infarction (MI) risk. We investigated the genetic predisposition of lipid metabolism influencing MI. The study dataset was from...

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Identifiers

PMID: 40089108
DOI: 10.1016/j.jlr.2025.100777
PMCID: PMC12004384

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