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A Western-style diet interacts with genetic variants of the LDL receptor to hyper-LDL cholesterolemia in Korean adults

23 Jul 2020

Abstract excerpt

OBJECTIVE: To evaluate the association of genetic risk scores (GRS) of LDLR, APOB and proprotein convertase subtilisin-kexin type 9 (PCSK9) SNP and plasma LDL concentrations and to identify lifestyle interactions with the GRS in Korean middle-aged adults. DESIGN: Korean genome and epidemiology study (KoGES) was conducted to determine genetic variants and lifestyle factors, including nutrient intakes, in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32698935
DOI: 10.1017/s1368980020001305

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