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Article

Prevalence, distribution, and mechanisms of genetic dominance in the yeast mating pathway.

Genetics - 6 Jul 2026

Allen M Grace, Martínez Artemiza A, Lang Gregory I

Abstract excerpt

The proportion of mutations that are dominant is a fundamental genetic parameter affecting the rate of adaptation, the efficacy of selection, and the maintenance of variation in populations. Yet, estimates for this parameter vary greatly. Here we directly quantify the rates and genetic targets of dominant and recessive mutations in the yeast mating pathway by performing parallel genetic screens in haploid (MATa)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42030123
DOI: 10.1093/genetics/iyag105
PMCID: PMC13334120

Genes

CLN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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