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Article

The cost of gene expression underlies a fitness trade-off in yeast.

Proceedings of the National Academy of Sciences of the United States of America - 7 Apr 2009

Lang Gregory I, Murray Andrew W, Botstein David

Abstract excerpt

Natural selection optimizes an organism's genotype within the context of its environment. Adaptations to one environment can decrease fitness in another, revealing evolutionary trade-offs. Here, we show that the cost of gene expression underlies a trade-off between growth rate and mating efficien...

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Share to Gene Expression Regulation, Fungal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Saccharomyces cerevisiae

Share to Selection, Genetic

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Identifiers

PMID: 19299502
DOI: 10.1073/pnas.0901620106
PMCID: PMC2658138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19299502-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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