The Desmoplakin Phenotype Spectrum: Is the Inflammation the "Fil Rouge" Linking Myocarditis, Arrhythmogenic Cardiomyopathy, and Uncommon Autoinflammatory Systemic Disease?

Abstract excerpt

Myocarditis is an inflammatory condition of cardiac tissue presenting significant variability in clinical manifestations and outcomes. Its etiology is diverse, encompassing infectious agents (primarily viruses, but also bacteria, protozoa, and helminths) and non-infectious factors (autoimmune responses, toxins, and drugs), though often the specific cause remains unidentified. Recent research has highlighted the...

Topics

• Humans
• Arrhythmias, Cardiac
• Cardiomyopathy, Dilated
• Desmoplakins
• Genetic Predisposition to Disease
• Inflammation
• Mutation
• Myocarditis
• Phenotype