Article
Identification of lipid quantitative trait loci linked with cardiometabolic disease in Asian Indians and Europeans: A genome-wide association study and Mendelian randomization.
PLoS medicine - 1 Apr 2026
Rout Madhusmita, Aston Christopher E, Duggirala Ravindranath, Goring Harald H, Fiehn Oliver, Sanghera Dharambir K
Abstract excerpt
BACKGROUND: Genetic mechanisms that predispose people to type 2 diabetes (T2D) and cardiovascular disease (CVD) remain poorly understood, partly because of a lack of sufficient data on non-European ethnic groups. Extending these evaluations to diverse cohorts is essential for gaining insights into the molecular pathways involved in disease development among human populations. In this study, we aimed to evaluate...
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