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Article

Low-density lipoprotein cholesterol and risk of COPD: a Mendelian randomization study.

Scientific reports - 15 Apr 2026

Justesen Josefine Freyberg, Wadström Benjamin Nilsson, Marott Sarah Caroline Weisenfeldt, Landt Eskild Morten, Nordestgaard Børge Grønne, Afzal Shoaib, Dahl Morten

Abstract excerpt

Statins have shown effects on exacerbation rates and lung function in individuals with chronic obstructive pulmonary disease (COPD) in randomized controlled trials. This has led to speculation that elevated LDL cholesterol may increase the risk of adverse COPD outcomes. We tested the hypothesis that high LDL cholesterol is causally associated with increased risk of severe COPD exacerbation, COPD-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41986588
DOI: 10.1038/s41598-026-48823-6
PMCID: PMC13237049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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