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Article

Association of smoking, lung function and COPD in COVID-19 risk: a two-step Mendelian randomization study.

Addiction (Abingdon, England) - 1 Jul 2022

Au Yeung Shiu Lun, Li Albert Martin, He Baoting, Kwok Kin On, Schooling C Mary

Abstract excerpt

BACKGROUND AND AIMS: Smoking increases the risk of severe COVID-19, but whether lung function or chronic obstructive pulmonary disease (COPD) mediate the underlying associations is unclear. We conducted the largest Mendelian randomization study to date, to our knowledge, to address these questions. DESIGN: Mendelian randomization study using summary statistics from genome-wide association studies (GWAS), FinnGen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35220625
DOI: 10.1111/add.15852
PMCID: PMC9111410

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