Article
Mendelian randomization study shows a causal effect of asthma on chronic obstructive pulmonary disease risk
1 Sept 2023
Abstract excerpt
BACKGROUND: This study was performed to explore the causal association between asthma and chronic obstructive pulmonary disease(COPD). METHODS: We obtained summary statistics for asthma from 408,442 Europeans in an open genome-wide association study (GWAS) from the UK Biobank to select strongly associated single nucleotide polymorphisms that could serve as instrumental variables for asthma (P < 5×10-8)....
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