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Article

Evolution and emergence of the integrase inhibitor 231 insertion resistance mutation in an HIV-2 strain isolated in central Portugal.

Virus genes - 1 Jun 2026

Pereira-Vaz João, Carmo Anália, Mendes Alexandra, Morais Célia, Alves Ana, Rodrigues Fernando, Duque Vítor

Abstract excerpt

Limited in vivo data are available regarding the recently described integrase (IN) codon 231 insertion mutation in Human immunodeficiency virus 2 (HIV-2) because this new resistance pathway to integrase strand transfer inhibitors (INSTIs) has only been found in very few clinical isolates. This study reports the emergence of the IN codon 231 insertion resistance mutation in an HIV-2 strain isolated from a person...

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PMID: 41984383
DOI: 10.1007/s11262-026-02236-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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