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Article

Resistance to HIV Integrase Inhibitors: About R263K and E157Q Mutations.

Viruses - 18 Jan 2018

Charpentier Charlotte, Descamps Diane

Abstract excerpt

The use of integrase inhibitors (INI) is increasing in antiretroviral therapies (ART) and INI are not all equal regarding genetic barrier to resistance. The aim of this manuscript was to review main in vivo and in vitro knowledge about two particular integrase resistance-associated mutations: R263K and E157Q. The R263K mutation was the first mutation rarely found selected at time of virological failure in...

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Identifiers

PMID: 29346270
DOI: 10.3390/v10010041
PMCID: PMC5795454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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