Article
Identification of a new 2-amino acid insertion in the integrase coding region of HIV-1 subtype G isolates.
Journal of medical virology - 1 Nov 2021
Pereira-Vaz João, Crespo Pedro, Mocho Luísa, Martinho Patrícia, Fidalgo Teresa, Correia Lurdes, Rodrigues Fernando, Duque Vítor
Abstract excerpt
Amino acid insertions have been rarely found in the integrase (IN) coding region of Human immunodeficiency virus 1 (HIV-1), and have been considered as natural polymorphisms. It is still unclear the potential impact of these insertion mutations on the viral replication capacity and/or susceptibility to integrase strand transfer inhibitors (INSTIs). The objective of this study was to describe a previously...
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