Article
Evaluation of HIV-1 integrase resistance emergence and evolution in patients treated with integrase inhibitors
19 Jul 2019
Abstract excerpt
OBJECTIVES: This study evaluated the emergence of mutations associated with integrase strand transfer inhibitors (INSTI) resistance (INSTI-RMs) and the integrase evolution in human immunodeficiency virus type 1 (HIV-1) infected patients treated with this drug class. METHODS: The emergence of INSTI-RMs and integrase evolution (estimated as genetic distance between integrase sequences under INSTI treatment and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
