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Article

HIV-2 integrase polymorphisms and longitudinal genotypic analysis of HIV-2 infected patients failing a raltegravir-containing regimen.

PloS one - 1 Jan 2014

Cavaco-Silva Joana, Abecasis Ana, Miranda Ana Cláudia, Poças José, Narciso Jorge, Águas Maria João, Maltez Fernando, Almeida Isabel, Germano Isabel, Diniz António, Gonçalves Maria de Fátima, Gomes Perpétua, Cunha Celso, Camacho Ricardo Jorge

Abstract excerpt

To characterize the HIV-2 integrase gene polymorphisms and the pathways to resistance of HIV-2 patients failing a raltegravir-containing regimen, we studied 63 integrase strand transfer inhibitors (INSTI)-naïve patients, and 10 heavily pretreated patients exhibiting virological failure while receiving a salvage raltegravir-containing regimen. All patients were infected by HIV-2 group A. 61.4% of the integrase...

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Identifiers

PMID: 24681625
DOI: 10.1371/journal.pone.0092747
PMCID: PMC3969368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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