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Article

Placental Histiocyte Phenotypes in Chronic Histiocytic Intervillositis: A Comprehensive Immunophenotypic and Morphologic Atlas.

International journal of molecular sciences - 26 Mar 2026

Gradhand Elise, Strahler Luisa, Bein Julia, Mijatovic Margarete, Hullmeine Hannah-Ida, Weigert Andreas, Spahn Stephan, Herrmann Eva, Bahlmann Franz, Hullmeine Ella

Abstract excerpt

Chronic histiocytic intervillositis (CHI) is a placental lesion characterized by an inflammatory response, significantly influencing maternal and fetal outcomes. This study aims to develop a comprehensive morphologic atlas detailing the localization of fetal and maternal macrophages within the context of CHI. We employed immunohistochemical and multiplexing techniques to analyze placental samples, identifying...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 41977213
DOI: 10.3390/ijms27073024
PMCID: PMC13072785

Genes

CD14
CD163
CD68

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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