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Article

Identification of a unique intervillous cellular signature in chronic histiocytic intervillositis

24 May 2023

Abstract excerpt

Chronic histiocytic intervillositis (CHI) is a rare histopathological lesion in the placenta characterized by an infiltrate of CD68+ cells in the intervillous space. CHI is associated with adverse pregnancy outcomes such as miscarriage, fetal growth restriction, and (late) intrauterine fetal death. The adverse pregnancy outcomes and a variable recurrence rate of 25–100% underline its clinical relevance. The...

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PMID: 37300938
DOI: 10.1016/j.placenta.2023.05.007

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